专利名称:REGULATED GENE EXPRESSION SYSTEMS
AND CONSTRUCTS THEREOF
发明人:TURNER, ROBERT J.,SERSHON,
VALERIE,AIKENS, JOHN,HOLZLE, DENISE
申请号:EP12764327申请日:20120326公开号:EP2689017A4公开日:20150603
摘要:The present disclosure is directed to compositions and methods for nitrogensensitive regulation of expression of a transcribable nucleic acid molecule. One aspectprovides a nitrogen-sensitive expression system that includes a transcription factorregion comprising an NtcA binding site and a core promoter region comprising a RuBisCopromoter or a variant or a functional fragment thereof. Another aspect provides amethod of transforming a host cell with an expression system. Also provided areexpression cassettes, transformed host cells, and kits.
申请人:PROTERRO, INC.
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